Download Clinical In Vitro Fertilization by Ann Westmore (auth.), Carl Wood CBE, FRCS, FRCOG, FRACOG, PDF

By Ann Westmore (auth.), Carl Wood CBE, FRCS, FRCOG, FRACOG, Alan Trounson MSc, PhD (eds.)

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Trounson et al. (1981b) are attempting to freeze-thaw human embryos. The reasons for attempting freeze-thawing are as follows. Transplantation of human embryos may not be possible because of cervical stenosis, uterine bleeding, severe pyrexia or other illness in the patient. As the technique of ET has been improved, the number of failed transfers has diminished. Despite this, failure does occur in 1 or 2 per 100 patients. Most infertility clinics use fertility drugs to increase the chances of conception in patients having IVF.

Most infertility clinics use fertility drugs to increase the chances of conception in patients having IVF. In our own experience, the chances of establishing pregnancy are high if multiple embryos are produced (Trounson et al. 1981a). For example, in a recent trial, pregnancy rates were 12%, 28% and 40% after the transfer of one, two or three embryos respectively. Using fertility drugs, there is a possibility of producing more eggs than are required by the patient. The number of eggs fertilized could be limited to the exact number the patient requires for transfer.

Excerpta Medica, Amsterdam Cohen J, Feinerman D, Palmer R, Rumeau-Rouquette C (1972) Results of a retrospective study on the outcome of tubal repair surgery in sterility. Acta Eur Fertil3: 321-338 Craft I, McLeod F, Green S, Djahanbakhch 0, Bernard A, Twigg H (1982) Human pregnancy following oocyte and sperm transfer to the uterus. 1033 Das Gupta P, Hickman L (1976) A note on the effect of ignoring dropout cases on fecundability as estimated from a follow-up study. J Theor Bioi 61: 411-417 Edwards RG (1981) Test-tube babies.

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