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5. High magnification of a lymph node in which virusinfected xenogenized tumor cells grow well. Ai**:'"- . ·■:*, \ Λ Fig. 6. The lymph node, however, begins to shrink, and tumor cells disappear gradually. 45 Fig. 7. Finally, the normal structure of the lymph node ap­ pears again. No perceptible signs exist that there was tumor metastasis in the lymph node. Fig. 8. A new antigen appearing on the cell surface as indi­ cated by granules of immunoferritin. There is a virus budding, and the new foreign antigen (arrows) that is produced on the surface after xenogenization may be recognized as foreign by the host.

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Exp. Cell Res. 30, 509-520. Weiss, L. (1965). Exp. Cell Res. 37, 540-555. Weiss, L. (1977). Int. J. Cancer 20, 87-92. Weiss, L. (1978). Jnt. J. Cancer 22, 196-203. , and Holmes, J. C. (1980). In "Proteinases and Tumor Invasion" (P. Sträuli, A. J. Barrett, and A. ), pp. 181-199. Raven, New York. , Rapp, D. , and Holmes, J. C. (1982). Br. J. Cancer 45, 44-53. Zeidman, I. ) (1982). B. , Wash­ ington , D. C. LEONARD WEISS AND OKHEE W. SUH 38 DISCUSSION COHEN: In your maps, the high-density cells tend to be at the periphery and clustered.

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